Plasmid-cured Salmonella enteritidis AL1192 as a candidate for a live vaccine.
نویسندگان
چکیده
We report the immunizing capacity of Salmonella enteritidis AL1192, a strain that has been cured of a 36-megadalton plasmid, to protect ddY mice against subsequent challenge with virulent salmonellas. This strain, which was given subcutaneously at a dose of 10(6) organisms, provided significant protection against oral, subcutaneous, or intraperitoneal challenge by virulent wild-type strains of not only S. enteritidis, but also S. dublin, S. naestved, and S. typhimurium.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 50 2 شماره
صفحات -
تاریخ انتشار 1985